Quality Inn I-75 At Exit 399

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Quality Inn I-75 At Exit 399 The Award Winning Quality Inn hotel off of I-75, Exit 399, in Alachua. 15 mins from Gainesville, FL!

One of the largest hotels in the Gainesville area, this Alachua, FL hotel is less than 15 miles from Ginnie Springs Outdoors Campground and Dive Resort, Shands at Vista hospital, and the VA Hospital. This Gainesville area hotel is 15 minutes from the University of Florida and Ben Hill Griffin Stadium at Florida Field. The Gainesville Regional Airport and Ichetucknee Springs State Park are 18 miles from the hotel. The Quality Inn hotel is only one mile from historic downtown Alachua, an area full of antique shops and restaurants. Within 5 miles of WalMart's Distribution Center and Progress Research Park.

10/23/2026

Oklahoma City offers a meal worth detouring for at the award-winning, Florence’s Restaurant. Dig into “grandma’s cooking” as you Check Into More on Route 66 with Choice Hotels.

📍Country Inn & Suites by Radisson, Oklahoma City

10/22/2026

Sweet or savory road trip snacks? Enjoy both—from the hotel waffle bar 🧇 to the unexpected 🍿 movie theater experience, go One More Mile with us across Route 66. Next stop, Odeon Theater in Tucumcari, NM.

📍Comfort Inn & Suites Amarillo East, Amarillo, TX

The recent hurricanes and storms are just a few of the more than 60,000 disasters the American Red Cross responds to eac...
10/22/2026

The recent hurricanes and storms are just a few of the more than 60,000 disasters the American Red Cross responds to each year. Help those affected by disasters big and small, whenever and wherever they occur across the country by donating Choice Privileges® points to the American Red Cross*.

Choice Privileges will extend our match point donations an extra $15,000, bringing our total matching to $30,000. http://ch.social/6182BHX3G6

10/16/2026

Check Into More on Route 66 with Choice Hotels as you visit to the historic Odeon Theater. From live performances and comedy shows to karaoke and video game tournaments, the theater gives audiences an unforgettable reason to make a detour.

📍Comfort Inn & Suites Amarillo East, Amarillo, TX

Cooler days call for a change of scenery. Save 15% on your stay of 2+ nights* when you book by November 16 and stay Octo...
10/16/2026

Cooler days call for a change of scenery. Save 15% on your stay of 2+ nights* when you book by November 16 and stay October 11 through November 30, 2026. Stay must begin Sunday–Thursday. http://ch.social/6180BHJAYp

*Terms apply.

Slow down, take a dip, and enjoy a little time to unwind.
10/16/2026

Slow down, take a dip, and enjoy a little time to unwind.

10/14/2026

Johnnie says it best—“Get out on the 2-lane road and see places like this!”

Plan your Route 66 road trip with a pit stop at The Classic Gas and Check Into More with Choice Hotels.

📍Casa de Suenos Old Town Historic Inn, An Ascend Collection Hotel, Albuquerque, NM

Start your day on a good note with a hearty morning and a fresh start.
10/14/2026

Start your day on a good note with a hearty morning and a fresh start.

A warm welcome starts the moment you walk through our doors. Come in, feel comfortable, and make yourself at home at Qua...
10/12/2026

A warm welcome starts the moment you walk through our doors.
Come in, feel comfortable, and make yourself at home at Quality Inn Alachua.

Slow down, soak up the sunshine, and enjoy the moment.
10/09/2026

Slow down, soak up the sunshine, and enjoy the moment.

Some stays are more than just a place to rest—they’re where the best memories begin. 🌿✨
10/07/2026

Some stays are more than just a place to rest—they’re where the best memories begin. 🌿✨

10/02/2026

Pumpkin spice and a weekend away, that’s nice. AARP members get 15% off* 2+ night stays. Stay 10/9–10/12. Book now at: http://ch.social/6181BGvxll

*Terms apply.

10/01/2026

Travel tip for anyone with food allergies or dietary restrictions 👇✈️

Having a kitchen where you’re staying can give you a lot more control over what you eat while you travel. At Suburban Studios, part of Choice Hotels Extended Stay, you can cook right in your room and even have groceries delivered so you don’t have to spend part of your trip shopping.

I made this easy meatless stuffed pepper skillet that happens to be vegetarian AND gluten-free. 🌱 Having the flexibility to make meals that work for you is just one more way to stay in your rhythm while you’re away from home.

Broaden your horizons and your options: Check out Suburban Studios, part of Choice Hotels Extended Stay, for your next trip!

Share the gift of travel. Members can now share Choice Privileges® points with other members to get them to their next r...
10/01/2026

Share the gift of travel. Members can now share Choice Privileges® points with other members to get them to their next reward faster! Learn more: http://ch.social/6187BGt4Mh

The best moments are the ones we share. Gather your favorite people, enjoy a relaxing stay, and create unforgettable mem...
09/30/2026

The best moments are the ones we share. Gather your favorite people, enjoy a relaxing stay, and create unforgettable memories at Quality Inn Alachua.

Come stay with us at Alachua Quality Inn and enjoy comfortable accommodations, friendly hospitality, and a convenient lo...
09/28/2026

Come stay with us at Alachua Quality Inn and enjoy comfortable accommodations, friendly hospitality, and a convenient location. Whether you’re traveling for business or leisure, we’re ready to make your stay a pleasant one.

Book your stay today!

Take a break, soak up the sunshine, and unwind by the pool at Quality Inn Alachua. Whether you’re cooling off or simply ...
09/25/2026

Take a break, soak up the sunshine, and unwind by the pool at Quality Inn Alachua. Whether you’re cooling off or simply enjoying a little downtime, your relaxing getaway starts here!

Get ready to set your OOO! ☀️🌊🏖️Save 25% on 3+ nights* in the Caribbean when you book 8/10–11/13 and stay 9/1–11/30/26. ...
09/24/2026

Get ready to set your OOO! ☀️🌊🏖️Save 25% on 3+ nights* in the Caribbean when you book 8/10–11/13 and stay 9/1–11/30/26. *Terms apply.

http://ch.social/6187BGdn33

09/23/2026

Check Into More on Route 66 and join us at the Classic Gas Museum, a one-of-a-kind spot that’ll inspire you to plan your own adventure. And when you do, Choice Hotels will help you rest and recharge along the way.

📍Casa de Suenos Old Town Historic Inn, An Ascend Collection Hotel, Albuquerque, NM

Start your day with a delicious breakfast in a warm and welcoming space at Quality Inn Alachua. Whether you're heading o...
09/23/2026

Start your day with a delicious breakfast in a warm and welcoming space at Quality Inn Alachua.

Whether you're heading out for a busy day or taking your time to enjoy the morning, we've got your day off to a great start!

09/21/2026

A 74-year-old, award-winning restaurant. An American travel museum. A private movie theater tour. Discover the history of Route 66 and Check Into More on the road.

Get inspired. Plan your next road trip, and stay with Choice Hotels.

From the moment you walk through our doors, we want you to feel right at home. At Quality Inn Alachua, enjoy a welcoming...
09/21/2026

From the moment you walk through our doors, we want you to feel right at home.

At Quality Inn Alachua, enjoy a welcoming atmosphere, comfortable accommodations, and friendly hospitality throughout your stay.

09/16/2026

From getting ready together to one more coffee before heading home, we’re here for every kind of celebration.

09/04/2026

Been thinking about using your PTO? Let this be your sign. ✨

Use your Choice Privileges® points and make your next getaway happen.

http://ch.social/20260904

Happy 110th b-day to the National Park Service! 🥳Celebrate by donating Choice Privileges® points to the National Park Fo...
08/21/2026

Happy 110th b-day to the National Park Service! 🥳Celebrate by donating Choice Privileges® points to the National Park Foundation & we’ll match up to $25k. Let’s preserve parks for generations to come. 🏔️🌲 🏜️ Learn more: http://ch.social/6181B1lcmR

Experience your college 🏈 team like never before with VIP experiences from Choice Privileges®. Bid points on exclusive a...
08/17/2026

Experience your college 🏈 team like never before with VIP experiences from Choice Privileges®. Bid points on exclusive access like pre-game sideline access, VIP hospitality and more. http://ch.social/6189B1wy5Z

Terms apply.

Address

15960 NW US Highway 441
Alachua, FL
32615

Telephone

+13864622244

Website

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