Residence Inn Jacksonville - Mayo Clinic Area

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Residence Inn Jacksonville - Mayo Clinic Area 155 guest rooms, all-suite extended stay hotel less than 1 mile to Mayo Clinic Jacksonville, FL. Free Shuttle to Mayo Clinic. Just 3 mi to the Atlantic Ocean.
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All of the comforts of home await you at our all-suite hotel in Jacksonville, Florida, ideally located near the Mayo Clinic with a complimentary shuttle, spacious suites with fully equipped kitchens, free breakfast, fitness center, and outdoor pool. Residence Inn Jacksonville - Mayo Clinic Area featuring fully equipped kitchens and living area.

10/28/2026

Residence Inn by Marriott gives the whole family space to start the day their own way ☕️💤

Road trip to Jacksonville calling your name? Beach days, zoo adventures and plenty of Jacksonville exploring await!🌴☀️🦒M...
10/27/2026

Road trip to Jacksonville calling your name? Beach days, zoo adventures and plenty of Jacksonville exploring await!🌴☀️🦒

Make your getaway even better with spacious accommodations, complimentary hot breakfast and perks that keep the adventure going, including:

⛽ $50 in gas cards
🚗 Complimentary parking
🗺️ City map
🎁 Welcome amenity
🥞 Complimentary hot breakfast

Use promo code: E4000 when booking your stay. Valid stay dates: now through December 31, 2026.

10/22/2026

Choose your player. Who are you on the family vacation? There’s room for everyone at Residence Inn by Marriott.

Have an exercise schedule you'd like to keep while visiting us? Our fitness center can help you keep your workouts going...
10/22/2026

Have an exercise schedule you'd like to keep while visiting us? Our fitness center can help you keep your workouts going strong away from home.

10/21/2026

With a full in-room kitchen in every suite, the whole family settles in like they’re at home. Which one are you? ☕

Stay, savor, and unwind. 🍽️🍷Make your next stay at Residence Inn Jacksonville even better with our Dine & Unwind offer. ...
10/19/2026

Stay, savor, and unwind. 🍽️🍷

Make your next stay at Residence Inn Jacksonville even better with our Dine & Unwind offer. Enjoy a $50 Food & Beverage credit to use at our on-site restaurant or lobby bar, whether you're relaxing after a busy day or treating yourself to a leisurely evening.

*The fine print: $50 F&B credit valid at our on-site restaurant and bar, valid any day of the week. Use promo code D60 when booking your stay. Valid now through December 31, 2026.

https://bit.ly/3Vf2zn7

Your home away from home in Jacksonville awaits. Settle in, get comfortable, and enjoy a relaxing stay with us.🛏️ Whethe...
10/17/2026

Your home away from home in Jacksonville awaits.

Settle in, get comfortable, and enjoy a relaxing stay with us.🛏️ Whether you’re here for a quick getaway or an extended stay, there’s nothing better than having a space that feels like your own.

10/14/2026

Enjoy a tasty meal and a refreshing cocktail at our Hotel Bar & Lounge. Nothing says vacation like enjoying something delicious and a relaxing moment.

Planning an upcoming event and looking for the perfect Jacksonville venue? Gather around the firepit under the stars, ce...
10/06/2026

Planning an upcoming event and looking for the perfect Jacksonville venue? Gather around the firepit under the stars, celebrate with friends and family, and enjoy the perfect setting for a memorable event.

Set the tone before the main event in our chic pre-function space. This is the perfect spot for stylish moments, cocktai...
10/03/2026

Set the tone before the main event in our chic pre-function space. This is the perfect spot for stylish moments, cocktails, conversations and a little pre-event excitement all come together. 🥂

09/29/2026

From unforgettable events to delicious catering, this is where memorable experiences come to life. 🥂🍽️

Pop into the Hotel Bar & Lounge inside Residence Inn Jacksonville Mayo Clinic Area for something tasty in a relaxing amb...
09/24/2026

Pop into the Hotel Bar & Lounge inside Residence Inn Jacksonville Mayo Clinic Area for something tasty in a relaxing ambiance. What are you craving today?

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Eat, drink, and be merry when you unwind with friends at Residence Inn by Marriott Columbus Downtown.Photo by ctheidel o...
12/29/2022

Eat, drink, and be merry when you unwind with friends at Residence Inn by Marriott Columbus Downtown.

Photo by ctheidel on IG

Let the warmth of Residence Inn by Marriott Breckenridge's lobby welcome you back after a day spent on the nearby slopes...
12/21/2022

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Take in the sights of South Beach and return to recharge in a fully-equipped guest room. 🌴Photo by jadelbrito on IG📍 Res...
12/13/2022

Take in the sights of South Beach and return to recharge in a fully-equipped guest room. 🌴

Photo by jadelbrito on IG
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Address

4905 San Pablo Road South
Jacksonville, FL
32224

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