Hilton Jacksonville Mayo Clinic Area

Hilton Jacksonville Mayo Clinic Area Jacksonville’s Iconic Host. Now open. Book now and share your stay at . Home to Coastal Kitchen.

Hilton Jacksonville at Mayo Clinic brings a new chapter of purpose-driven hospitality to Northeast Florida. Located just one mile from Mayo Clinic’s renowned campus, our full‑service flagship hotel merges wellness, design, and convenience. Perfect for medical travelers, families, business guests, and explorers of Jacksonville. Key features:
Prime location: 4745 Transformation Way, under 1 mile to

the Mayo Clinic, 4 miles to UNF, 5 miles to the beaches, and 6 miles to St. Johns Town Center

Seamless arrival:
Onsite self‑parking, on‑site EV charging, free Wi‑Fi throughout public spaces. Warm & restorative amenities:
Outdoor pool, fitness center, in‑room dining, and Coastal Kitchen restaurant, all crafted with guest's well‑being in mind. Flexible spaces:
Over 21,000 sqft of indoor and outdoor venues, ideal for meetings, wellness retreats, or family celebrations

Guest‑centric service:
Concierge, digital check‑in/key, and Hilton CleanStay standards for a safer, seamless stay

Our 8‑story, 252‑room hotel is officially open, reservations at
https://www.hilton.com/en/hotels/jaxmohh-hilton-jacksonville-at-mayo-clinic/

Last week to share your experience. is in the Condé Nast Traveler Readers' Choice Awards, and the people who stayed wit...
06/23/2026

Last week to share your experience.

is in the Condé Nast Traveler Readers' Choice Awards, and the people who stayed with us are the ones who get to weigh in.

Voting closes June 30. Cast your vote at https://ow.ly/itlq50Z6Vk0

06/21/2026

Summer at is built your way.

Coastal Cool Escape brings an oceanside beach setup, a snack box, and two cocktails at Coastal Kitchen & Bar when you stay two or more nights Thursday through Monday.

Sun & Peach State of Mind sends Florida and Georgia residents home with a $50 gas gift card and complimentary parking on a three-night stay.

Book your chosen stay at https://ow.ly/tUPo50Z6VhH

Stay three nights, get half off the third with our Stars, Stripes, & Sun package, from July 2 to 7.Live music poolside F...
06/20/2026

Stay three nights, get half off the third with our Stars, Stripes, & Sun package, from July 2 to 7.

Live music poolside Friday night, a 250th Cookout Bash Saturday from 11 AM to 3 PM, and daily happy hour at all weekend long.

Book your 4th of July stay at https://ow.ly/M3Zl50Z6VaC

Some moments deserve more than four walls.Cocktails on the lawn, dinner by the water, and a team that anticipates every ...
06/17/2026

Some moments deserve more than four walls.

Cocktails on the lawn, dinner by the water, and a team that anticipates every detail.

is built to host iconic celebrations. Start planning yours at https://ow.ly/oVeV50Z6UYo

On June 26, turns your Friday into something worth planning for. Tacos and Tequila Night runs from 5:30 PM to 7 PM wit...
06/15/2026

On June 26, turns your Friday into something worth planning for.

Tacos and Tequila Night runs from 5:30 PM to 7 PM with interactive stations, an exclusive menu, a Bellagave Tequila tasting and create your own margarita experience, and giveaways.

$50 per person. Learn more and get your ticket at https://ow.ly/cswT50Zc3Bo

On June 26, turns your Friday into something worth planning for. Tacos and Tequila Night runs from 5:30 PM to 7 PM wit...
06/15/2026

On June 26, turns your Friday into something worth planning for.

Tacos and Tequila Night runs from 5:30 PM to 7 PM with interactive stations, an exclusive menu, a Bellagave Tequila tasting and create your own margarita experience, and giveaways.

$50 per person. Learn more and get your ticket at https://ow.ly/5H6l50Z6TQE

06/11/2026

Somewhere between check-in and last call, the right bar changes the pace of the entire stay.

Coastal Kitchen & Bar was recognized as the Best Hotel Bar in Jacksonville by Jacksonville Magazine for the Best in Jax 2026.

Come see what earned us the title at .

Dad deserves a real Sunday.A brunch buffet at $42 with bottomless beermosas on the pour and a Mojo Flank Steak and Eggs ...
06/08/2026

Dad deserves a real Sunday.

A brunch buffet at $42 with bottomless beermosas on the pour and a Mojo Flank Steak and Eggs special at $28.95.

Sunday, June 21, from 10 AM to 2 PM at inside . Reserve your table now at https://ow.ly/oSw050Z6TC6.

Out-of-towner, or hometowner, the Coastal Cool Escape package meets you where you are.Two or more nights Thursday throug...
06/07/2026

Out-of-towner, or hometowner, the Coastal Cool Escape package meets you where you are.

Two or more nights Thursday through Monday unlock a beach setup, a snack box to take with you, and two cocktails at Coastal Kitchen & Bar

Book your stay at https://ow.ly/4nYB50Z6Tq2

If your stay stood out, you can vote for Hilton Jacksonville at Mayo Clinic in the Condé Nast Traveler Readers’ Choice A...
06/05/2026

If your stay stood out, you can vote for Hilton Jacksonville at Mayo Clinic in the Condé Nast Traveler Readers’ Choice Awards.

Each vote enters you for a chance to win a 15-day Viking ocean voyage with a four-night stay in Oxford and Hampshire.

Voting is open through June 30. Cast your vote at https://ow.ly/sWSO50YZ5Zk.

Address

4745 Transformation Way
Jacksonville, FL
32224

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