Holiday Inn Express & Suites San Diego Otay Mesa

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Holiday Inn Express & Suites San Diego Otay Mesa The newly renovated Holiday Inn Express & Suites San Diego Otay Mesa welcomes you! The International Commercial Border Crossing is .25 miles away.

This choice San Diego hotel is nestled in the heart of the Otay Mesa Industrial Business Park, a short drive from Downtown San Diego and less than 1 mile from beautiful Tijuana, Mexico. We offer a convenient suburban location near the Cross Border Xpress, North Island Credit Union Amphitheatre, SeaWorld Aquatica, SeaWorld, the Chula Vista Olympic Training Park and the famous San Diego Zoo. Learn about local history at the Cabrillo National Monument, the Air and Space Museum and the Maritime Museum, or visit us for fun annual events such as Comic Con. Check out Las Americas Premium Outlets with 125 outlet stores and 13 restaurants in a lovely outdoor setting, or try the Otay Town Center Mall, just four miles from our hotel. Business travelers will enjoy a stay at our San Diego hotel because of its convenient location near companies such as Toyota, Bose, Panasonic, Maxwell, Tyco, JVC, Siemens Medical and Samsung, each within six miles of our hotel in the Otay Mesa Industrial Park. The Brown Field Municipal Airport is three miles away. During your stay, enjoy a free hot breakfast, Fitness Center and outdoor pool. Check out our San Diego hotel room deals to start planning your trip today.

10/20/2026

Sweet, savory, stackable, spoonable… wherever you wake up, there’s something tasty to get out of bed for.

A stay that loves your to-do AND your do-not-disturb.
10/15/2026

A stay that loves your to-do AND your do-not-disturb.

10/06/2026

A winning blend: Costa Coffee and Holiday Inn Express.

09/29/2026

Morning motivation comes standard: Free hot breakfast and Costa Coffee at Holiday Inn Express.

*Offerings vary by region.

09/25/2026

Keep rolling, we’ve got you covered. Everything you need to rest, recharge, and fuel up is ready at Holiday Inn Express by IHG.

09/23/2026

We saved you a spot. It’s next to the cinnamon rolls.

*Offerings vary by region.

09/21/2026

*Books stay for breakfast*

*Offerings vary by region.

It's love at first sip. *Offerings vary by region.
09/19/2026

It's love at first sip.

*Offerings vary by region.

09/17/2026

Game day’s sweetest start.

*Offerings vary by region.

09/16/2026

Wherever you travel, we're there. Cheering you on.

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean ...
08/31/2026

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean spaces, so you can snooze with confidence.

08/30/2026

Our REM cycle runs on pancakes. Dreamy breakfast + Costa Coffee, free at Holiday Inn Express.

*Offerings vary by region.

Address

2296 Niels Bohr Court
San Diego, CA
92154

Telephone

+16197100900

Website

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